Access, Greek sites, regulatory developments and Greek research participation — only when genuinely relevant.
Greece
Access, Greek sites, regulatory developments and Greek research participation — only when genuinely relevant.
If you are considering a trial from Greece
This is a practical route to verify access; it is not a recommendation to join a study.
1. Open the official recordUse ClinicalTrials.gov or CTIS, rather than a news item or social post.
2. Check location and eligibilityConfirm the country and named site, recruitment status, contact details and inclusion criteria.
3. Discuss it with your care teamA neurologist can help put eligibility, potential burden, standard treatment and safety in context. The study site makes the final eligibility decision.
ACCESS IN GREECE
No myelin-repair study on the current watchlist is recruiting in Greece
Registry cross-checkHuman trials • ClinicalTrials.gov plus CTIS
The current check of active and upcoming clinical programmes tracked by MyelinWatch found no registered recruiting site in Greece. Recruiting studies are currently located in countries including the Netherlands, France and the United States, while MACSiMiSE-BRAIN is active but not recruiting in Belgium.
What this means clinically
For someone in Greece, a global Recruiting label does not mean a Greek centre is available. Location, eligibility and direct contact with the trial site still need to be checked.
Source quality: High for status and locations • official registries
The ACT-1004-1239 study in progressive MS is active in CTIS and examines MRI, electrophysiological and biochemical remyelination endpoints. CTIS lists one participating country and one site: the Netherlands.
What this means clinically
This is an important European trial for the field, but it is not currently a recruitment option through a Greek centre and there are no clinical-benefit results yet.
OCTOPUS: the Stage 1 metformin/ALA analysis is the next major progressive-MS readout
UK platform • analysis in progressHuman Phase 3 platform • result pending
OCTOPUS scheduled its first interim analysis for September 2026, with a go/no-go decision for the initial arms around October. It includes metformin and alpha-lipoic acid and now assesses clinical measures alongside MRI.
What this means clinically
A positive Stage 1 signal would matter to people with progressive MS internationally, including Greece. It is not a final Phase 3 result or proof that metformin repairs disability.
Source quality: High for trial status • official OCTOPUS/UCL update
New Fleming/NKUA study examines fibronectin and failed myelin repair
Preclinical • not a treatment for patientsPeer-reviewed PNAS • cells and animal models
Researchers including teams from BSRC Alexander Fleming and the National and Kapodistrian University of Athens described a mechanism in which fibronectin accumulation may trap OPCs in demyelinated lesions. Fibronectin inhibition improved remyelination in experimental models.
What this means clinically
This is important Greek participation in basic and translational research, not an available treatment or human trial. There is no evidence of clinical benefit in people.
Source quality: High for a preclinical finding • peer-reviewed primary paper